Blog Posts Breast Cancer Research: The Breakthroughs of Today for Those Diagnosed Tomorrow October 24 | 2 mins As one of the largest foundations in the world, the Breast Cancer Research Foundation (BCRF) funded nearly 300 scientists from 2018 to 2019. The research conducted by these past, current and future grantees will create opportunities, solutions and breakthroughs for breast cancer patients. Thanks to the research on this disease, there are more than 3.5 million breast cancer survivors in the U.S and deaths from breast cancer have declined by 40 percent over the last 25 years. A Legacy of Breakthroughs In 1999, BCRF discovered that the drug Tamoxifen, an anti-estrogen drug, could be used to treat early and advanced stages of the disease to reduce the incidence of breast cancer by about 30%. Four years later, they identified cancer stem cells in breast cancer to help prevent progression and metastasis. In 2012, a new drug Perjeta was approved to be used in combination with other medication and chemotherapy to improve the overall survival of metastatic breast cancer from the average of 40 months to 56 Imonths. TAILORx Trial: Avoiding Chemotherapy in Early Stages of the Disease In 2018, after 10 years of research, the ‘TAILORx trial’ confirmed that most patients with early stage ER-positive breast cancer (which is nearly 60,000 patients per year), can skip chemotherapy. By determining an Oncotype DX® Recurrence Score® through 21 genes from a tumor biopsy, patients are assigned a Reoccurrence Score (RS) of 1-100. The RS indicates the likelihood of the cancer returning and determines the risk of recurrence in newly diagnosed patients while in the early stages of the disease. The study included more than 10,000 women across 6 countries with ER-positive, HER2-negative, node negative breast cancer. The women with a low RS (RS of 1-10) were treated with hormone therapy alone, and the women with a high-risk of recurrence (RS greater than 26) were treated with a combination of hormone therapy and chemotherapy. Of the total study participants, 70 percent were in an intermediate group with a RS of 11-25. In this group, participants were randomized to receive either hormone therapy and chemotherapy, or hormone therapy alone. The objective was to determine whether the addition of chemotherapy improved disease-free survival for this group of women. After seven and a half years of follow up, the trial concluded that hormone treatment, alone, was as effective in providing distant recurrence and overall survival as the patients that received hormone therapy plus chemotherapy. This is a breakthrough in breast cancer research because withholding or postponing the effects of chemotherapy treatment can improve a woman’s treatment plan, quality of life and spirit. The Breast Cancer Research Foundation continues to focus efforts on improving outcomes and advancements in personalized therapy. While there currently is no cure for this disease, the results of this research trial will provide hope to many women diagnosed in the future. **Content updated May 7, 2021 share this post Other Posts You Might Like read more Blog Posts Wake Up and Workout – Why Morning Exercise is Better for You March 21 | 3 mins read more Blog Posts Five Large Contributions Women Made in Healthcare March 7 | 3 mins read more Blog Posts Why Annual Physicals Are a Vital Preventative Care Element March 1 | 3 mins read more Blog Posts Investing in Employee Benefits Education is Beneficial to Both Employees and Employers January 30 | 2 mins read more Blog Posts Health Benefits Education and Direct Primary Care Can Lower Costs for Self-Funded Groups January 30 | 3 mins read more Blog Posts Americans are Five Times More Likely to Experience Increased Stress Levels During the Holidays December 20 | 2 mins read more Blog Posts How Benefit Design Can Help Employers Remain Competitive December 7 | 2 mins read more Blog Posts Prediabetes: When to Worry About the Precursor to Diabetes November 17 | 3 mins read more Blog Posts An Affordable Healthcare Alternative for Non-Benefited Employees April 25 | 3 mins read more Blog Posts Direct Primary Care is a Win for Brokers, Employers, and Employees February 22 | 2 mins read more Blog Posts A New Healthcare Offering for Uninsured Children February 18 | 3 mins read more Blog Posts Hope for Escalating Healthcare Costs February 18 | 2 mins read more Blog Posts Give Employers an Affordable Complement to HDHPs February 18 | 3 mins read more Blog Posts DPC: A No-Claims Approach to Essential Primary Care February 11 | 3 mins read more Blog Posts What Employees Really Want in a Job January 31 | 3 mins read more Blog Posts Solutions to Alleviate Financial Worries in Healthcare January 24 | 2 mins read more Blog Posts DPC Addresses Cumulative Effects of Inflation and Escalating Health Insurance Costs January 17 | 3 mins read more Blog Posts Addressing Healthcare Deserts with Affordable Solutions January 10 | 3 mins read more Blog Posts A New Approach to Customized Benefits January 3 | 2 mins read more Blog Posts Employee Well-Being is the New Normal December 6 | 2 mins read more Blog Posts The U.S. Ranks Last in Healthcare Equity and Affordability Among High-Income Nations November 17 | 2 mins read more Blog Posts Diabetes Awareness Can Save Lives [Affordable Access to Healthcare Can Help Detect, Treat and Manage Chronic Diseases Such as Diabetes] November 8 | 3 mins read more Blog Posts Benefits as a Recruitment Strategy [Cost-Effective Solutions Such As Direct Primary Care Provide Customizable Benefits] September 20 | 3 mins read more Blog Posts The Importance of Health Screenings [Direct Primary Care Memberships Provide Access to Routine Healthcare] September 15 | 3 mins read more Blog Posts Helping Employees Understand Their Benefits September 2 | 2 mins read more Blog Posts The Consequences of Delaying Medical Care August 18 | 2 mins read more Blog Posts Major Shifts in Healthcare [Implementing Long-Term Strategies for Telemedicine and Virtual Care] August 4 | 2 mins read more Blog Posts Why Millennials Ignore Health Issues July 19 | 2 mins read more Blog Posts Anti-Aging Secrets: An Unexpected Benefit of Primary Care? July 2 | 3 mins read more Blog Posts Creative Healthcare Solutions for States with the Least Coverage June 23 | 2 mins read more Blog Posts Three Overlooked Groups Looking for Innovative Healthcare Solutions [How Direct Primary Care Can Address Their Needs] June 15 | 3 mins read more Blog Posts Data-Driven Insights for Building Better Health Plans June 9 | 3 mins read more Blog Posts DPC Practices Seek to End Disparities in Healthcare May 27 | 3 mins read more Blog Posts The Relationship Between Physical Health and Mental Health [How to Promote Better Physical and Mental Wellbeing] May 19 | 2 mins read more Blog Posts Primary Care Counteracts the Negative Impact of Poor Economic Conditions on Health April 27 | 2 mins read more Blog Posts Two Accelerating Contributors to Health Inequity [How Medication Insecurity and Healthcare Homelessness Calls for Better Access to Primary Medical Care] April 22 | 3 mins read more Blog Posts Health Plan Design is a Strategic Business Decision April 1 | 3 mins read more Blog Posts Increased Demand for Virtual Healthcare Going Forward March 19 | 3 mins read more Blog Posts Chronic Disease Management Provides Big ROI March 10 | 2 mins read more Blog Posts Be Prepared for the New Normal Through the Power of Partnerships March 2 | 4 mins read more Blog Posts Looking into Healthcare’s Crystal Ball – The Present and Future of Direct Primary Care February 19 | 4 mins read more Blog Posts Affordable Healthcare Alternatives Can Minimize the Fallout from COVID February 12 | 3 mins read more Blog Posts Affordable Healthcare and Financial Literacy for Millennials [How Direct Primary Care Delivers the On-Demand Healthcare Experience that Millennials Want] February 3 | 3 mins read more Blog Posts Direct Primary Care Helps Address Healthcare Inequality for Children [Accessible and Unlimited Primary Care] January 26 | 3 mins read more Blog Posts Role of Direct Primary Care in Healthcare Equality [How Affordable and convenient care isn’t just a tagline] January 21 | 3 mins read more Blog Posts The Small Businesses Healthcare Revolution December 7 | 3 mins read more Blog Posts 3 Reasons You Should Be Having as Much Fun as Possible November 2 | 3 mins read more Blog Posts Nextgen Solutions to Keep Families Healthy September 28 | 3 mins read more Blog Posts The Future of Primary Care [ How the Primary Care Landscape is Adapting to a Mobile Workforce ] September 25 | 2 mins read more Blog Posts The ABCs of DPC – The Building Blocks of Healthcare [ What is Direct Primary Care and Why is it Important? ] September 22 | 4 mins read more Blog Posts Caregiver Burnout: Tips for Self-Care [How to care for yourself so you can care for others] September 14 | 2 mins read more Blog Posts Optimal Cholesterol Levels Help Maintain Optimal Health August 28 | 2 mins read more Blog Posts Celebrating Women’s Contributions to Healthcare August 20 | 3 mins read more Blog Posts Healthcare for the Service Sector August 6 | 3 mins read more Blog Posts Prepare for a New Normal July 30 | 3 mins read more Blog Posts Tips for a Happy and Healthy Summer July 24 | 3 mins read more Blog Posts A Solution for Disparities in Healthcare July 17 | 3 mins read more Blog Posts 3 Ways Artificial Intelligence is Changing Healthcare July 8 | 3 mins read more Blog Posts Prevention is the Best Strategy for Chronic Disease July 6 | 2 mins read more Blog Posts Healthcare2U Launches Redesigned Website to Better Support Brokers, Employers and Members June 26 | 2 mins read more Blog Posts Doctors Love Direct Primary Care June 16 | 3 mins read more Blog Posts Is There Such a Thing as Balance? May 29 | 3 mins read more Blog Posts Men Visit the Doctor Less Than Women May 12 | 2 mins read more Blog Posts Hidden Causes of Hypertension May 12 | 3 mins read more Blog Posts Solutions for Anxiety and Depression May 12 | 3 mins read more Blog Posts The Importance of Primary Care May 12 | 3 mins read more Blog Posts DPC Will Be Crucial for Health Plans Going Forward May 6 | 3 mins read more Blog Posts Tips to Stay Fit at Home April 29 | 2 mins read more Blog Posts The Connection Between Health and Friendship April 20 | 3 mins read more Blog Posts Stress Relief in Times of Uncertainty April 14 | 2 mins read more Blog Posts 3 Powerful Ways to Boost Your Immune System April 1 | 3 mins read more Blog Posts COVID-19: Tips to Stay Safe and Healthy March 25 | 3 mins read more Blog Posts How Employee Burnout Increases Healthcare Costs March 25 | 2 mins read more Blog Posts Coronavirus: Stay Calm and Aware, But Don’t Panic March 25 | 3 mins read more Blog Posts The Link Between Technology and Depression March 25 | 2 mins read more Blog Posts Finding Solutions for Surprise Medical Billing March 25 | 3 mins read more Blog Posts 3 Ways Love Can Improve Your Health March 25 | 2 mins read more Blog Posts How Physical Fitness Benefits Mental Health March 25 | 2 mins read more Blog Posts Tips for a Happy and Healthy Holiday Season March 25 | 2 mins read more Blog Posts Five Ways to Reduce The Risk of Back Pain March 25 | 2 mins read more Blog Posts Five Factors Contributing to Childhood Obesity March 25 | 3 mins read more Blog Posts Five Things Employers Should Consider When Looking for a Direct Primary Care Provider March 25 | 3 mins read more Blog Posts National Women’s History Month: Five Influential Women in Medicine March 11 | 3 mins read more Blog Posts Heart Failure Awareness Week February 11 | < 1 min read more Blog Posts Our Hearts are Healthier Together February 5 | 2 mins read more Blog Posts Employers Seek Alternative Solutions to Solve Rising Benefit Plan Costs January 28 | 2 mins read more Blog Posts The Real Impact of Chronic Diseases in America January 21 | 4 mins read more Blog Posts Conquering Your New Year’s Resolutions December 20 | 2 mins read more Blog Posts Winter Wellness December 20 | 2 mins read more Blog Posts Employer Provided Healthcare Isn’t Making the Cut December 20 | < 1 min read more Blog Posts Breast Cancer Research: The Breakthroughs of Today for Those Diagnosed Tomorrow October 24 | 2 mins read more Blog Posts Breast Cancer Facts and Myths October 10 | < 1 min read more Blog Posts Fighting a Killer September 28 | 3 mins read more Blog Posts 7 Ways to Celebrate Women’s Health & Fitness Day September 26 | 3 mins read more Blog Posts The Fight Against Childhood Obesity September 10 | 3 mins read more Blog Posts Five Tips to Prepare for a Healthier School Year August 22 | 2 mins read more Blog Posts Sticking to a Healthy Eating Plan over the Holidays and into the New Year November 29 | 2 mins read more Blog Posts Focus on Diabetes – Preventing a Killer November 1 | 3 mins read more Blog Posts Direct Primary Care Delivering Lower Costs, Better Patient Experience October 12 | 3 mins read more Blog Posts Savings 101: Healthcare strategies for self-funded companies September 12 | 2 mins read more Blog Posts Embarking on a Path to Health and Wellness August 22 | 3 mins read more Blog Posts The Rise of Telemedicine July 25 | 2 mins read more Blog Posts What is a Healthcare Advocate? October 7 | 2 mins CONTACT US BECOME A PART OF THE SOLUTION Redefine the healthcare experience with No-Claims Healthcare™ Contact us